Postdoc Position in Detection and Quantification of Rnas and Their Modifications From Long Read[]

Postdoc Position in Detection and Quantification of RNAs and Their Modifications from Long Read Sequencing Data Commitment & contract: _ At IIT, we are committed to advancing human-centered Science and Technology to address societal challenges. We foster excellence in fundamental and applied research across fields like neuroscience, humanoid technologies, AI, nanotechnology, and materials science, offering an interdisciplinary scientific experience. Our approach integrates cutting-edge tools and technology, empowering researchers to push the limits of knowledge and innovation. With us, your curiosity will know no bounds. We are dedicated to providing equal employment opportunities and fostering diversity in all its forms, creating an inclusive environment. We value the unique experiences, backgrounds, cultures, and perspectives of our people. By embracing diversity, we believe science can achieve its fullest potential. THE ROLE GENOMIC SCIENCE The Research Unit is coordinated by Dr. Francesco Nicassio, an expert in genomics and non-coding RNA biology. Our lab focuses on cancer genomics, development, and stem cells, particularly on the role of noncoding RNA transcripts. Our research integrates computational methodologies, emphasizing the reciprocal regulation of coding and non-coding RNAs. Representative publications include: RNA modifications detection by comparative Nanopore direct RNA sequencing - Nat Commun., 2021, doi.org/10.1038/s41467-021-27393-3 Nanopore ReCappable sequencing maps SARS-CoV-2 5′ capping sites and provides new insights into the structure of sgRNAs Benchmarking of computational methods for m6A profiling with Nanopore direct RNA sequencing - Brief Bioinform. Unveiling the role of PUS7-mediated pseudouridylation in host protein interactions specific for the SARS-CoV-2 RNA genome - Mol Ther Nucleic Acids, 2023, doi.org/10.1016/j.omtn.2023.102052, PMID: 38028201 MAIN RESPONSIBILITIES Develop computational methods and analytical strategies to characterize non-coding RNA biology and RNA modifications in various biological contexts, including epigenetic regulation, gene expression control, microRNA biogenesis, and mechanisms of cancer progression and chemo-resistance. Coordinate and co-supervise junior lab members, participate in meetings, and disseminate research findings. ESSENTIAL REQUIREMENTS PhD in a natural sciences discipline (Biology, Biotechnology, Mathematics, Physics, or similar). Experience in genomics, bioinformatics, and scientific programming in R or Python. Strong data analysis skills and basic understanding of statistics. Ability to organize and report data effectively. Proficiency in spoken and written English. Teamwork skills and high motivation to learn. Experience with Nanopore sequencing. ADDITIONAL SKILLS Knowledge of RNA modifications biology. Experience with bioinformatics workflow tools like Nextflow or Snakemake. Good communication skills, problem-solving attitude, and creativity. Ability to work independently and in a highly interdisciplinary environment. COMPENSATION PACKAGE Competitive salary according to international standards. Wide range of staff discounts. Location: MILANO SEMM Position: Postdoc Organization: Genomic Science Job Posting Date: Feb 17, 2025, 4:06:50 AM J-18808-Ljbffr

Location: provincia-di-milano, IT

Posted Date: 6/17/2025